Table 2.
The minimum inhibitory concentration (MIC) of CAMPs
| CAMPs | CAMP-t1 | CAMP-t2 | CAMP-A | CAMP-B | AvBD-6 |
|---|---|---|---|---|---|
| Bacteria (strain identification) |
MIC (μg/ml) | MIC (μg/ml) | MIC (μg/ml) | MIC (μg/ml) | MIC (μg/ml) |
| P. aeruginosa (ATCC 27853) | 64 | 64 | 16 | 32 | > 256 |
| P. aeruginosa (1704173) a | 128 | 64 | 16 | 32 | > 256 |
| P. aeruginosa (1703357) a | 128 | 128 | 16 | 64 | > 256 |
| P. aeruginosa (1703511) a | 128 | 128 | 16 | 64 | > 256 |
| P. aeruginosa (1703000) a | 128 | 64 | 8 | 32 | > 256 |
| P. aeruginosa (1703002) a | 128 | 256 | 16 | 64 | > 256 |
| P. aeruginosa (1703451) a | 128 | 64 | 16 | 64 | > 256 |
| P. aeruginosa (1703949) a | 128 | 128 | 16 | 64 | > 256 |
| P. aeruginosa (1703290) a | 128 | 128 | 16 | 64 | > 256 |
| P. aeruginosa (1703983) a | 128 | 256 | 16 | 64 | > 256 |
| P. aeruginosa (1704175) a | 128 | 64 | 16 | 32 | > 256 |
| MICAverage G- | 122.18 ± 19.29a | 122.18 ± 72.71a | 15.27 ± 2.41c | 52.36 ± 16.14b | > 256 |
| S. aureus (ATCC 29213) | 64 | 64 | 32 | 32 | 256 |
| S. pseudintermedius(13164006)b | 256 | 32 | 16 | 32 | > 256 |
| S. pseudintermedius(13203008)b | 256 | 32 | 16 | 64 | 256 |
| S. pseudintermedius(13178007)b | 256 | 64 | 16 | 64 | 256 |
| S. pseudintermedius(13267017)b | 128 | 32 | 16 | 32 | > 256 |
| S. pseudintermedius(13252001)b | 64 | 32 | 16 | 32 | 256 |
| S. pseudintermedius(13269013)b | 256 | 32 | 32 | 32 | > 256 |
| S. pseudintermedius(13193006)b | 256 | 128 | 32 | 32 | > 256 |
| S. pseudintermedius(13228005)b | 256 | 32 | 16 | 64 | > 256 |
| S. pseudintermedius(13207007)b | 256 | 32 | 16 | 64 | > 256 |
| S. pseudintermedius(13250111)b | 256 | 32 | 32 | 64 | 256 |
| MICAverage G+ | 209.45 ± 81.41a | 46.55 ± 29.89b | 21.82 ± 8.07c | 46.55 ± 16.71b | ≥256 |
aMultidrug resistant clinical isolates of P. aeruginosa were resistant to chloramphenicol, tetracycline, sulfamethoxazole, and β-lactam antibiotics: amoxicillin, ampicillin and cefazolin.
bMethicillin-resistant S. pseudintermedius (MRSP)
Superscripts a, b, and c mean significant difference (p < 0.05) between MICs of four CAMPs against either Gram-negative or Gram-positive bacteria