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. 2018 Jun 6;6:48. doi: 10.1186/s40425-018-0368-0

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Representative multiplex immunofluorescences and PD-L1 expression in non-NCT and NCT. (Left) Multiplex immunofluorescence images of representative NSCLC tumor sections analyzed for panel 1 and panel 2 markers: upper images are from the group that did not receive neoadjuvant chemotherapy (non-NCT), while the lower images are from the group that did receive NCT. The images reflect the variations in cell phenotypes observed in these cases. (Right) Box plot showing that PD-L1 expression by malignant NSCLC cells was higher in the group that received NCT than in the non-NCT group. Images ×200