Figure 2.
The inter-membrane distance D can fluctuate. The perpendicular distance between two cell surfaces was changed between Dmin and Dmax within the range of ΔD (a). We tested the relation between domain numbers of tested CAM models and the number of trans-dimers formed along simulations under different ranges of inter-membrane fluctuations (b). We show that CAMs with more extracellular domains are more likely to bind to each other, while larger scale membrane fluctuations facilitate this process.