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. Author manuscript; available in PMC: 2018 Jul 1.
Published in final edited form as: J Oral Facial Pain Headache. 2017 Summer;31(3):264–274. doi: 10.11607/ofph.1803

Fig. 2.

Fig. 2

Inhibition of PKA signaling in the STN repressed CFA-induced increase in PKA immunoreactive levels. Representative images of sections from the STN obtained at the 2 hour time point from naïve, CFA injected, or CFA injection and intrathecal administration of KT5720 animals stained for the active form of PKA (green) are shown in the top panels. The same images co-stained for the expression of Iba1(red) are presented in the lower panels. The average change in relative staining intensity from naïve levels for PKA at 2 hours, 7 days, and 21 days after injections is reported. Data are reported as a fold-change ± SEM from levels in naïve animals, whose mean was made equal to one. * P < .05 when compared to naïve control levels and # P < .05 when compared to CFA levels. Scale bar = 100 μm.