Table 4.
Lambert et al | Progression CDR_SB Analysis | |||||||
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SNP | CHR | Gene | Major/Minor | MAF | OR/Beta | P.Value | Beta | P.Value |
rs10498633 | 14 | SLC24A4-RIN3 | G/T | 0.203 | 0.91/−0.09 | 5.50×10−09 | −0.01 | 0.07 |
rs11218343 | 11 | SORL1 | T/C | 0.040 | 0.77/−0.26 | 9.70×10−15 | −0.19 | 0.06 |
rs6733839 | 2 | BIN1 | C/T | 0.409 | 1.22/0.19 | 6.90×10−44 | 0.28 | 0.48 |
rs10792832 | 11 | PICALM | G/A | 0.335 | 0.87/−0.14 | 9.30×10−26 | −0.001 | 0.97 |
rs7274581 | 20 | CASS4 | T/C | 0.099 | 0.88/−0.12 | 2.50×10−08 | 0.09 | 0.21 |
rs28834970 | 8 | PTK2B | T/C | 0.364 | 1.1/0.09 | 7.40×10−14 | 0.08 | 0.06 |
rs10838725 | 11 | CELF1 | T/C | 0.296 | 1.08/0.08 | 1.10×10−08 | −0.04 | 0.39 |
rs10948363 | 6 | CD2AP | A/G | 0.279 | 1.1/0.09 | 5.20×10−11 | 0.04 | 0.34 |
rs35349669 | 2 | INPP5D | C/T | 0.476 | 1.08/0.08 | 3.20×10−08 | 0.06 | 0.12 |
rs11771145 | 7 | EPHA1 | G/A | 0.353 | 0.9/−0.11 | 1.10×10−13 | −0.04 | 0.35 |
rs983392 | 11 | MS4A6A | A/G | 0.358 | 0.9/−0.11 | 6.10×10−16 | −0.06 | 0.12 |
rs3865444 | 19 | CD33 | C/A | 0.279 | 0.94/−0.06 | 3.00×10−06 | −0.04 | 0.37 |
rs17125944 | 14 | FERMT2 | T/C | 0.104 | 1.14/0.13 | 7.90×10−09 | −0.001 | 0.89 |
rs1476679 | 7 | ZCWPW1 | T/C | 0.263 | 0.91/−0.09 | 5.60×10−10 | 0.004 | 0.92 |
rs2718058 | 7 | NME8 | A/G | 0.361 | 0.93/−0.07 | 4.80×10−09 | −0.04 | 0.38 |
rs8093731 | 18 | DSG2 | C/T | 0.029 | 0.73/−0.31 | 1.00×10−04 | −0.05 | 0.71 |
rs4147929 | 19 | ABCA7 | G/A | 0.177 | 1.15/0.14 | 1.10×10−15 | 0.03 | 0.61 |
rs6656401 | 1 | CR1 | G/A | 0.197 | 1.18/0.17 | 5.70×10−24 | −0.006 | 0.93 |
rs9331896 | 8 | CLU | T/C | 0.379 | 0.86/−0.15 | 2.80×10−25 | −0.43 | 0.28 |
rs9271192 | 6 | HLA-DRB5-HLA-DRB1 | A/C | 0.276 | 1.11/0.14 | 2.90×10−12 | NA | NA |
rs190982 | 5 | MEF2C | A/G | 0.408 | 0.93/−0.07 | 3.20×10−08 | 0.04 | 0.59 |
rs769449 | 19 | APOE | G/A | - | - | - | 0.06 | 0.21 |
SNP, based on Build 37 of reference genome. MAF, Minor allele frequency. NA no data available.