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. Author manuscript; available in PMC: 2019 Jan 1.
Published in final edited form as: J Alzheimers Dis. 2018;62(2):745–756. doi: 10.3233/JAD-170834

Table 4.

Hits from Lambert that could be related to progression in AD for CDR-SB

Lambert et al Progression CDR_SB Analysis

SNP CHR Gene Major/Minor MAF OR/Beta P.Value Beta P.Value
rs10498633 14 SLC24A4-RIN3 G/T 0.203 0.91/−0.09 5.50×10−09 −0.01 0.07
rs11218343 11 SORL1 T/C 0.040 0.77/−0.26 9.70×10−15 −0.19 0.06
rs6733839 2 BIN1 C/T 0.409 1.22/0.19 6.90×10−44 0.28 0.48
rs10792832 11 PICALM G/A 0.335 0.87/−0.14 9.30×10−26 −0.001 0.97
rs7274581 20 CASS4 T/C 0.099 0.88/−0.12 2.50×10−08 0.09 0.21
rs28834970 8 PTK2B T/C 0.364 1.1/0.09 7.40×10−14 0.08 0.06
rs10838725 11 CELF1 T/C 0.296 1.08/0.08 1.10×10−08 −0.04 0.39
rs10948363 6 CD2AP A/G 0.279 1.1/0.09 5.20×10−11 0.04 0.34
rs35349669 2 INPP5D C/T 0.476 1.08/0.08 3.20×10−08 0.06 0.12
rs11771145 7 EPHA1 G/A 0.353 0.9/−0.11 1.10×10−13 −0.04 0.35
rs983392 11 MS4A6A A/G 0.358 0.9/−0.11 6.10×10−16 −0.06 0.12
rs3865444 19 CD33 C/A 0.279 0.94/−0.06 3.00×10−06 −0.04 0.37
rs17125944 14 FERMT2 T/C 0.104 1.14/0.13 7.90×10−09 −0.001 0.89
rs1476679 7 ZCWPW1 T/C 0.263 0.91/−0.09 5.60×10−10 0.004 0.92
rs2718058 7 NME8 A/G 0.361 0.93/−0.07 4.80×10−09 −0.04 0.38
rs8093731 18 DSG2 C/T 0.029 0.73/−0.31 1.00×10−04 −0.05 0.71
rs4147929 19 ABCA7 G/A 0.177 1.15/0.14 1.10×10−15 0.03 0.61
rs6656401 1 CR1 G/A 0.197 1.18/0.17 5.70×10−24 −0.006 0.93
rs9331896 8 CLU T/C 0.379 0.86/−0.15 2.80×10−25 −0.43 0.28
rs9271192 6 HLA-DRB5-HLA-DRB1 A/C 0.276 1.11/0.14 2.90×10−12 NA NA
rs190982 5 MEF2C A/G 0.408 0.93/−0.07 3.20×10−08 0.04 0.59
rs769449 19 APOE G/A - - - 0.06 0.21

SNP, based on Build 37 of reference genome. MAF, Minor allele frequency. NA no data available.