. Author manuscript; available in PMC: 2018 Jun 6.

Published in final edited form as: Ann Neurol. 2014 Apr 14;75(4):469–486. doi: 10.1002/ana.24132

TABLE 1.

Neuroimaging Modalities for Analysis of Different Types of Brain Injury in Preterm Survivors

Modality	Examples of Specialized Analyses	Types of Data Acquired
High-resolution MRI	Volumetrics, deformation-based morphometry	Volumes and growth of cortical and subcortical brain structures
DTI	Region of interest–based analyses, tract-based spatial statistics, tractography	Brain microstructure, myelination
MTR		Myelination
MRSI		Measures of regional brain metabolites reflecting regional brain development and injury including N-acetyl-aspartate and lactate
FCMRI		Map of the developing brain connectome including pathways relevant to specific functional outcomes, such as motor and vision control, as well as “resting state” network

DTI = diffusion tensor imaging; FCMRI = functional connectivity MRI; MRI = magnetic resonance imaging; MRSI = magnetic resonance spectroscopy and spectroscopic imaging; MTR = magnetization transfer ratio.