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. Author manuscript; available in PMC: 2018 Aug 6.
Published in final edited form as: Ann Intern Med. 2017 Dec 12;168(3):170–178. doi: 10.7326/M17-0537

Appendix Table 2.

Comparison of Patient Characteristics From Multiple Imputation Data Sets

Variable Imputation 1 Imputation 2 Imputation 3 Imputation 4 Imputation 5





Mean SE Mean SE Mean SE Mean SE Mean SE
Age, y 61.99 0.63 61.99 0.63 61.99 0.63 61.99 0.63 61.99 0.63

Female, % 0.50 0.02 0.50 0.02 0.50 0.02 0.50 0.02 0.50 0.02

Black race, % 0.17 0.04 0.17 0.04 0.17 0.04 0.17 0.04 0.17 0.04

HbA1c level, % 7.39 0.10 7.38 0.10 7.38 0.10 7.39 0.10 7.39 0.10

Duration of diabetes, y 9.71 0.42 9.71 0.42 9.71 0.42 9.71 0.42 9.71 0.42

Current smoker, % 0.17 0.02 0.17 0.02 0.17 0.02 0.17 0.02 0.17 0.02

Body mass index, kg/m2 32.78 0.54 32.77 0.53 32.77 0.54 32.81 0.55 32.82 0.53

Low-density lipoprotein cholesterol, mmol/L 2.59 0.06 2.53 0.06 2.63 0.05 2.59 0.05 2.58 0.05

High-density lipoprotein cholesterol, mmol/L 1.20 0.01 1.20 0.01 1.19 0.02 1.19 0.01 1.19 0.02

Hemoglobin level, g/dL 13.72 0.12 13.72 0.12 13.72 0.12 13.72 0.12 13.72 0.12

Leukocyte count, × 1000 cells/μL 7.45 0.14 7.45 0.14 7.45 0.14 7.45 0.14 7.45 0.14

Heart rate, beats/min 73.15 0.94 73.11 0.96 73.27 0.96 73.38 0.97 73.19 0.96

Systolic blood pressure, mm Hg 130.12 0.89 129.82 0.89 129.76 0.92 129.60 0.89 129.72 0.93

Estimated glomerular filtration rate, mL/min/1.73 m2 78.51 1.02 78.84 1.09 78.71 1.08 79.05 1.30 78.55 1.03

Albuminuria, % 0.19 0.03 0.19 0.03 0.19 0.03 0.19 0.03 0.19 0.03

Metformin, % 0.56 0.04 0.56 0.04 0.56 0.04 0.56 0.04 0.56 0.04

Sulfonylurea, % 0.35 0.04 0.35 0.04 0.35 0.04 0.35 0.04 0.35 0.04

Thiazolidinedione, % 0.08 0.02 0.08 0.02 0.08 0.02 0.08 0.02 0.08 0.02

Dipeptidyl peptidase-4 inhibitor, % 0.09 0.02 0.09 0.02 0.09 0.02 0.09 0.02 0.09 0.02

Glucagon-like peptide-1 receptor agonist, % 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00 0.00

Meglitinide, % 0.02 0.01 0.02 0.01 0.02 0.01 0.02 0.01 0.02 0.01

α-Glucosidase inhibitor, % 0.01 0.00 0.01 0.00 0.01 0.00 0.01 0.00 0.01 0.00

Insulin, %

 Basal 0.18 0.03 0.18 0.03 0.18 0.03 0.18 0.03 0.18 0.03

 Short-acting bolus 0.11 0.01 0.11 0.01 0.11 0.01 0.11 0.01 0.11 0.01

 Medium-acting bolus 0.02 0.01 0.02 0.01 0.02 0.01 0.02 0.01 0.02 0.01

HbA1c = glycated hemoglobin.