Table 3.
Observational studies examining outcomes after parathyroidectomy in patients with kidney transplants
| Study | Country | Sample Size, PTx/Medical Treatment | Mean Age, yr | Women, % | Dialysis Duration before Kidney Transplant, mo | Median Time to PTx after Transplant, mo | Mean Duration of Follow-Up, mo | Study Period | Mean Serum iPTH, pg/ml | Mortality and Allograft Outcomes |
|---|---|---|---|---|---|---|---|---|---|---|
| Evenepoel et al., 2007 (60) | Belgium | 90/1653 | 50.9 | 50.0 | 47.7 | 11.0 | 62.6 (From time of transplant) | 1989–2004 | 107.1 | Mortality difference; ↑ Cr 1.76–1.91 in first month after PTx; no long-term Cr difference |
| Ivarsson et al., 2015 (59) | Sweden | 156/892 | 51.9 | 50.0 | 61.2 | Not reported | 76.9 (From time of PTx) | 1991–2009 | Not reported | No mortality difference |
A consistent association with improved survival was observed in the dialysis population across studies. PTx, parathyroidectomy; iPTH, intact parathyroid hormone level; Cr, creatinine.