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. Author manuscript; available in PMC: 2018 Jun 6.
Published in final edited form as: Cancer Cell. 2012 Sep 11;22(3):373–388. doi: 10.1016/j.ccr.2012.07.016

Figure 1. Phenotypical Characterization of Docetaxel-Resistant Cells.

Figure 1

(A) Genes with at least 1.8-fold increase ↑ or decrease ↓ in transcript expression comparing parental and Docetaxel-resistant cells.

(B) Gene ontology categories of overlapping genes. Categories with statistical significance (p ≤ 0.01) are represented. *GO categories related to cell proliferation, cell death, and response to drugs. **GO categories related to developmental processes. ***GO category related to antigen presentation.

(C) Heatmap illustrates epithelial differentiation, prostate specific, HLAI, and developmental (Notch and Hedgehog) gene expression of parental and Docetaxel-resistant cells.

(D) Immunoblotting and quantification of parental and Docetaxel-resistant cells for indicated proteins. SCaBER was used as a positive control for high molecular weight cytokeratins and p63.

(E) Immunofluorescent staining of parental and Docetaxel-resistant cells for indicated proteins.

See also Figure S1.