Table 1.

Estimated Nodule VDT by Slice Thickness and Various Observed Nodule Growth Patterns^*

	Growth, d
Patterns	From 4–5 mm	From 5–6 mm	From 4–6 mm	From 4–8 mm	From 9–10 mm
Observed nodule diameter growth over 90 d
VDT median	93	114	51	30	197
VDT 95% CI
0.625/1.25 mm	86–102	106–124	49–53	29–31	189–206
2.50 mm	65–159	81–183	42–64	27–33	163–248
5.00 mm	59–190	76–215	40–68	26–34	157–264
Observed nodule diameter growth over 180 d
VDT median	186	228	103	60	395
VDT 95% CI
0.625/1.25 mm	171–205	211–248	98–107	59–61	378–413
2.50 mm	128–314	163–367	84–128	54–67	326–497
5.00 mm	119–380	153–430	80–136	52–68	313–529
Observed nodule diameter growth over 360 d
VDT median	373	457	205	120	789
VDT 95% CI
0.625/1.25mm	342–409	422–496	197–214	117–123	756–826
2.50 mm	258–631	325–732	167–257	107–134	653–994
5.00 mm	239–760	305–853	159–272	104–137	626–1,061

^*Note that the estimated VDT medians are equal, what would be predicted by the modification of Lindell et al ¹² of the tumor growth model of Schwartz ¹³ using the diameters and times of interest.