Table 4.
Test | FRDA (SD) | Controls (SD) | Effect size | P |
---|---|---|---|---|
MOCA | 22.3 (3.6) | 26.2 (2.3) | 0.33 | <0.001 |
Pointing names | 23.9 (0.3) | 24 (0.2) | 0.02 | 0.301 |
Naming nouns | 13.9 (1.3) | 14.2 (1.2) | 0.01 | 0.568 |
RCPM | 29.6 (6.3) | 33 (5.4) | 0.08 | 0.050 |
Digit Span | 7 (4.4) | 6.5 (1.1) | 0.01 | 0.454 |
SPART | 18.5 (6.6) | 22.9 (3.8) | 0.12 | 0.017 |
SPART‐D | 6.5 (2.4) | 8.2 (1.8) | 0.13 | 0.012 |
RAVLT | 40.8 (12.6) | 47.5 (9.4) | 0.08 | 0.052 |
RAVLT‐D | 9.3 (3.9) | 10.5 (3.4) | 0.03 | 0.250 |
SLD | 26.9 (2.2) | 28.5 (1.7) | 0.18 | 0.003 |
Mental rotation | 93.3 (15.9) | 105.8 (4.7) | 0.15 | 0.008 |
SDMT | 35.8 (10) | 57.3 (13.6) | 0.50 | <0.001 |
Attentional matrices | 50.5 (8.7) | 55.5 (3.2) | 0.05 | 0.118 |
TMT‐A | 67 (68.9) | 29.8 (8.8) | 0.27 | <0.001 |
TMT‐B | 127.3 (57.7) | 73.2 (24.2) | 0.33 | <0.001 |
Brief Stroop test | 50.1 (20.3) | 26.9 (7.4) | 0.44 | <0.001 |
Semantic fluency | 18.5 (5.8) | 23.7 (4.9) | 0.25 | 0.001 |
Phonemic fluency | 27.5 (11.7) | 41.3 (8.8) | 0.31 | <0.001 |
Significance shows the P value of the Mann–Whitney U test. FRDA, Friedreich ataxia patients; HC, healthy controls; MOCA, Montreal Cognitive Assessment; RCPM, Raven Colored Progressive Matrices; SPART, 10/36 Spatial Recall Test; SPART‐D, SPART delayed; RAVLT, Rey Auditory Verbal Learning Test Immediate Recall; RAVLT‐D, RAVLT Delayed Recall; SLD, Segment Length Discrimination; SDMT, Symbol Digit Modalities Test; TMT, Trail Making Test. Significant differences are reported in bold.