Table 1.
RV1 Non-responders | RV1 Responders | p-value | Dutch infants | p-values (NL-NR; NL-R) | |
---|---|---|---|---|---|
N | 10/66 (15%) | 10/66 (15%) | NA | 10 | NA |
Gender | 0.65 | ||||
Male | 6/10 (60%) | 5/10 (50%) | 6/10 | 1.0; 0.65 | |
Female | 4/10 (40%) | 5/10 (40%) | 4/10 | ||
RV1 dosing | 0.82 | ||||
6/10 wks | 1/10 (10%) | 2/10 (20%) | NA | ||
10/14 wks | 1/10 (10%) | 1/10 (10%) | |||
6/10/14 wks | 8/10 (80%) | 7/10 (70%) | |||
Rotavirus Season | 1.000 | NA | |||
Yes | 4/10 (40%) | 4/10 (40%) | |||
No | 6/10 (60%) | 6/10 (60%) | |||
Location of delivery | 0.64 | ||||
Home | 4/10 (40%) | 3/10 (30%) | 4/10 | 1.0; 0.64 | |
Healthcare | 6/10 (60%) | 7/10 (70%) | 6/10 | ||
Mode of delivery | 1.00 | ||||
Vaginal | 9/10 (90%) | 9/10 (90%) | 10/10 | 0.29; 0.29 | |
C-section | 1/10 (10%) | 1/10 (10%) | 0/10 | ||
Feeding | 1.00 | ||||
Breastfeeding | 9/10 (90%) | 9/10 (90%) | 7/10 | 0.35; 0.35 | |
BF + Formula | 1/10 (10%) | 1/10 (10%) | 2/10 | ||
Formula | 0/10 (0%) | 0/10 (0%) | 1/10 | ||
Malnutrition | |||||
(Z score<−2) | |||||
Length-for-age | 1/10 (10%) | 1/10 (10%) | 1.00 | 0/10 | 0.22; 0.22 |
Weight-for-length | 1/10 (10%) | 1/10 (10%) | 0/10 | ||
Weight-for-age | 1/10 (10%) | 1/10 (10%) | 0/10 |
Note. Baseline characteristics of the infants enrolled in the nested study and differences between the Pakistani RV1 non-responders and responders as determined by the Chi-square test. Baseline characteristics of the matched Dutch infants and differences between Dutch and Pakistani RV1 non-responders and responders, respectively as determined by the Chi-square test. Abbreviations: RV1, Rotavirus vaccine; NL, Dutch infants.