Figure 1. A-macB inhibits the viability of NSCLC cell lines. (A) The structure of A-macB. (B) Growth inhibition effects of A-macB on seven NSCLC cell lines and the mouse embryo fibroblast cell line NIH3T3. (C) IC₅₀ curves for H1299, A549 and NIH3T3 treated with A-macB for 72 h. (D) Proliferation inhibition curves of H1299, A549 and NIH3T3 incubated with A-macB for different times and at different concentrations. (E) Colony formation of NSCLC and the normal NIH3T3 cells treated with A-macB. Data are presented as the mean ± SEM (*p < 0.05, **p < 0.01, ***p < 0.001).