Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Mar 24;8(3):339–348. doi: 10.1016/j.apsb.2018.02.001

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2018 Chinese Pharmaceutical Association and Institute of Materia Medica, Chinese Academy of Medical Sciences. Production and hosting by Elsevier B.V.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Fig. 3 — (A) The interactions between the DIR sulfonate and M8V_L show the two orientations of the bound DIR in the crystal structure (green and yellow), and the A (light blue) and B (blue) V_L chains. CDR2 is colored pink. Ser^B56 and Arg^A53 also sample two alternate conformations. One sulfonate (top) has more interactions with the protein than the alternate (bottom) sulfonate. Adapted with permission from Ref. 20. Copyright (2012) American Chemical Society. (B) MG interactions with L5*. Spatial distribution of amino acid side chains that contact MG. Shown are contacting side chains from both V_L A (black letters) and V_L B (red letters) that comprise a set of pairwise symmetrical locations and orientations. Adapted with permission from Ref. 21.