Figure 2.

Performance of gene pair signatures 3‐GPS and 5‐GPS in identifying high‐risk colon cancer patients. The Kaplan‐Meier curves of disease‐free survival (DFS) for the high‐ and low‐risk groups of patients with right‐sided colon cancer (RCC) and left‐sided colon cancer (LCC) predicted by 3‐GPS and 5‐GPS in the discovery cohort (A) and validation cohort (C). (B,D) Multivariate Cox analysis. (E‐L) Kaplan‐Meier curves of DFS for responders (R) and non‐responders (NR) in patients treated with non‐adjuvant chemotherapy (ACT). B1, batch1, GSE14333; B2, batch2, GSE72970; CI, confidence interval; dMMR, MMR‐deficient; F, female; HR, hazard ratio; M, male; MMR, mismatch repair; Mut, mutation; pMMR, MMR‐proficient