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Mutation analysis of MED12, TP53 and PTEN and comparison with the literature for 6 types of uterine smooth muscle tumors
| Mutations | LMS | STUMP | Atypical LM | Cellular LM | Mitotically active LM | LM | Number of references |
|---|---|---|---|---|---|---|---|
| MED12 | 15% (21/141) | 10% (4/40) | 12% (8/69) | 12% (11/95) | 48% (16/33) | 67% (636/948) | 13 |
| TP53 | 28% (50/176) | 17% (6/35) | 10% (5/50) | 0% (0/26) | 0% (0/7) | 0% (0/59) | 7 |
| PTEN | 54% (76/142) | 33% (6/18) | 26% (11/42) | 5% (1/22) | 0% (0/7) | 5% (1/20) | 6 |
LM, leiomyoma; LMS, leiomyosarcoma.
