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. 2018 Mar 30;8(3):320–338. doi: 10.1016/j.apsb.2018.03.010

Figure 9.

Fig. 9

(a) Confocal fluorescence microscopy images of KB cells treated with mFLAME–FA or mFLAME–PEG with or without folic acid for 4 h. (λex = 635 nm and λex = 660–760 nm, Scale bar: 10 μm); (b) Illustration of the experimental procedure for the MRI detection of mFLAME–FA in KB cells; (c) 1H/19F MR images of KB cells treated with mFLAME–FA or mFLAME–PEG. The matrix size was 64 × 64, slice thickness was 30 mm, and RARE factor was 16. TE,eff and TR were 40 and 1000 ms, respectively. The number of average was 128. The acquisition time is 34 min 20 s. Scale bar: 0.3 μm (Adapted from the Ref. 67 with permission. Copyright©2015 the Royal Society of Chemistry).