. Author manuscript; available in PMC: 2018 Jun 6.

Published in final edited form as: Invest Ophthalmol Vis Sci. 2008 May 30;49(11):5077–5082. doi: 10.1167/iovs.08-1837

Table 2.

HLA-C Allele Groups (C1, C2), Cw*07 and Cw*0701 Allele Frequencies in Southampton AMD and Control Groups

HLA-C Alleles	AMD Group n = 104 (%)	Control Group n = 93 (%)	P^*	OR^†	95% CI
C1C1	43 (41.3)	46 (49.4)	0.25	0.72	0.41–1.27
C1C2	50 (48.1)	34 (36.6)	0.10	1.60	0.91–2.84
C2C2	11 (10.6)	13 (14.0)	0.46	0.73	0.31–1.71
C1 alleles	136 (65.4)	126 (67.7)	0.38	1.16	0.82–1.64
C2 alleles	72 (34.6)	60 (32.3)	0.14	1.44	0.88–2.39
Cw*07 allele	63 (60.1)	46 (49.5)	0.11	1.57	0.89–2.76
Cw*0701 allele	43 (41.3)	25 (26.9)	0.03^‡	1.92	1.05–3.50

Two-sided P values using χ² test.

^†

OR according to the approximation of Woolf. χ² for trend testing all C groups = 0.23 (P = 0.62).

^‡

Significant results.