Table 4.
HLA-C and KIR Receptor Paired Genotype Frequencies in Southampton AMD and Control Groups
| HLA + KIR Genotypes |
AMD Group n = 104 (%) |
Control Group n = 93 (%) |
P* | OR† | 95% CI |
|---|---|---|---|---|---|
| C1 group + 2DL2 | 37 (35.6) | 43 (46.2) | 0.12 | 0.64 | 0.36–1.14 |
| C1 group + 2DL3 | 87 (83.7) | 77 (82.8) | 0.87 | 1.06 | 0.50–2.25 |
| C1 group + 2DS2 | 37 (35.6) | 45 (48.4) | 0.07 | 0.59 | 0.33–1.04 |
| Cw*07 + 2DL2 | 27 (26.0) | 27 (29.0) | 0.62 | 0.86 | 0.46–1.60 |
| Cw*07 + 2DL3 | 62 (59.6) | 43 (46.2) | 0.06 | 1.71 | 0.97–3.02 |
| Cw*07 + 2DS2 | 28 (26.9) | 29 (31.2) | 0.51 | 0.81 | 0.44–1.50 |
| Cw*0701 + 2DL2 | 19 (18.3) | 14 (15.1) | 0.54 | 1.26 | 0.59–2.68 |
| Cw*0701 + 2DL3 | 18 (17.3) | 24 (25.8) | 0.14 | 0.60 | 0.30–1.20 |
| Cw*0701 + 2DS2 | 20 (19.2) | 15 (16.1) | 0.57 | 1.23 | 0.59–2.59 |
Two-sided P; χ2 test.
OR according to the approximation of Woolf.