Table 2.

Baseline plasma concentrations (μM) of D-serine and L-serine in MDD patients classified as responders (Rs) or non-responders (NRs) to treatment with (R,S)-ketamine

Patient no.	D-Ser	Rs L-Ser	Patient no.	D-Ser	NRs L-Ser
1	2.77	34.6	9	5.44	273.6
2	2.86	37.0	10	5.98	325.4
3	2.78	40.4	11	4.86	345.1
4	3.18	40.1	12	5.15	282.6
5	2.69	46.5	13	5.01	229.8
6	3.07	48.3	14	4.29	242.9
7	3.22	50.6	15	4.67	237.7
8	3.57	232.1	16	3.79	217.8
			17	5.05	228.3
			18	5.63	253.5
			19	3.77	226.4
			20	3.60	233.5
			21	3.57	61.4
Average	3.02*	66.2*		4.68	242.9
SD	0.30	62.8		0.81	67.2
SE	0.04	9.6		0.07	5.6

The data are presented as average, standard deviation (SD) and standard error (SE). The data from Rs were compared to the corresponding data from NRs using an unpaired Student’s t test (two-tailed). See text for experimental details

^*p<0.001