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. Author manuscript; available in PMC: 2018 Jun 6.
Published in final edited form as: Psychol Med. 2017 Jul 17;48(1):142–154. doi: 10.1017/S0033291717001635

Figure 2. Within-condition Group Differences in Peak Activation.

Figure 2

A) During breathing load anticipation, the RAN group showed reduced activation in the right mid-insula compared with controls. RAN participants deactivated right mid-insula during aversive interoceptive stimulus anticipation, whereas healthy controls activated this region. B) During breathing load, the RAN group showed increased activation compared with controls in bilateral PCC, right dACC, bilateral IFG and left MFG, left putamen, and right caudate. C) After breathing load, the RAN group showed increased activation compared with controls in bilateral anterior insula, mid-insula, and posterior insula, (graph shown for right mid-insula), bilateral caudate and putamen (graph shown for right putamen), left amygdala, bilateral PCC, bilateral ACC, bilateral IFG and left MFG, bilateral putamen and caudate, and bilateral amygdala. Error bars represent standard error of the mean. When multiple clusters are shown, the graphs correspond to circled clusters. RAN, women remitted from anorexia nervosa; CW, healthy control women; PCC, posterior cingulate cortex; IFG, inferior frontal gyrus; MFG, middle frontal gyrus; dACC, dorsal anterior cingulate cortex; amy, amygdala.