Figure 2.
Differential expression in response to chronic ethanol for microglia and total homogenate. A. Volcano plot showing log2 fold-change against log10 p-value. Differentially expressed genes (p < .05) are shown as green or blue dots. The top 20 differentially expressed genes are labeled. The total homogenate has larger fold-changes and lower p-values than the microglia. B. Venn Diagram showing the number of unique and overlapping differentially expressed genes (p < .05) in each of the preparations. 164 genes were differentially expressed with alcohol in both the microglia and total homogenate. Of these 164 genes, 44% (72 genes) were changed in different directions in the two preparations.