Figure 4.
Microglial module 3 (MGM3) was selected for further investigation based on its differential expression, biological function, and microglial specificity. A. MGM3 shows increased expression with chronic ethanol consumption (p < .05, Kruskal-Wallis Rank Sum Test). B. Genes contained in MGM3 are associated with several GO Biological Processes related to innate immune signaling. C. When compared to other CNS cell types, MGM3 shows highest relative expression of microglial genes (p < .05, ANOVA). D. When compared to other immune cell types, MGM3 shows highest relative expression of microglial genes (p < .05, ANOVA).