Table 3.
Cingulo-opercular network function and obsessive-compulsive disorder (OCD) severity
| ERRORS | ||||||
|---|---|---|---|---|---|---|
| pMFC | Left aI/fO | Right aI/fO | ||||
| Intercept | 1.70 ± .34 | <.001 | 1.91 ± .23 | <.001 | 1.99 ± .25 | <.001 |
| CYBOCS | −.08 ± .04 | .025 | −.05 ± .03 | .124 | ------------ | --- |
| Age | .14 ± .09 | .139 | .12 ± .08 | .142 | .29 ± .11 | .013* |
| Inc RT | ------------ | --- | ------------ | --- | ------------ | --- |
| Inc Acc | 12.66 ± 3.65 | .001* | 10.09 ± 3.40 | .005* | 7.68 ± 3.59 | .038 |
| CY-BOCS × Age | −.02 ± .01 | .079 | ------------ | --- | ------------ | --- |
| Motion | ------------ | --- | ------------ | --- | 9.91 ± 3.44 | .006* |
| Adjusted R-Square | .30 | .18 | .18 | |||
| Model ANOVA | F(4,46)=6.3 (p<.001) | F(3,47)=4.8 (p=.005) | F (3,47) = 4.6 (.006) | |||
| INTERFERENCE | ||||||
| pMFC | Left aI/fO | Right aI/fO | ||||
| Intercept | .57 ± .07 | <.001 | .35 ± .08 | <.001 | .42 ± .09 | <.001 |
| CY-BOCS | −.007 ± .01 | .478 | −.03 ± .01 | .009* | ------------ | --- |
| Age | .02 ± .03 | .504 | .01 ± .03 | .798 | .07 ± .03 | .043 |
| Overall RT | ------------ | --- | ------------ | --- | ------------ | --- |
| Overall Acc | −3.69 ± 1.81 | .045 | ------------ | --- | ------------ | --- |
| CY-BOCS × Age | −.006 ± .004 | .097 | −.008 ± .004 | .055 | ------------ | --- |
| Motion | 1.43 ± .76 | .065 | ------------ | --- | ------------ | --- |
| Adjusted R-Square | 0.09 | 0.15 | 0.05 | |||
| Model ANOVA | F(5,63)=2.3 (p=.048) | F(3,65)=4.0 (p=.012) | F(1,67)=4.3 (p=.043) | |||
Note: Motion refers to framewise displacement 28. Dashed lines represent predictor variables eliminated during backwards stepwise regression.
Significance levels were p < .05 for pMFC (primary region of interest, bolded) and p < .013 for secondary ROIs (asterisked).
Acc = accuracy, aI/fO = anterior insula/frontal operculum, CY-BOCS = Child Yale- Brown Obsessive Compulsive Scale, Inc = incongruent, pMFC = posterior medial frontal cortex, RT = Response time