Table 1.
Parasite/Disease | Drug | First line or Alternative | Adult Dose | Pediatric Dose |
---|---|---|---|---|
Intestinal nematodes | ||||
Hookworm | Albendazole | First line | 400 mg single dose | 1-2 years: 200 mg single dose |
≥2 years: 400 mg single dose | ||||
Pyrantel pamoate | Alternative | 11 mg/kg of pyrantel base (up to 1 g) daily for 3 days | ||
Ascaris lumbricoides | Albendazole | First line | 400 mg single dose | |
Ivermectin | Alternative | 150-200 µg/kg single dose | ||
Nitazoxanide | Alternative | 500 mg twice daily for 3 days | 1-3 yearsb: 100 mg twice daily for 3 days | |
4-11 yearsb: 200 mg twice daily for 3 days | ||||
Pyrantel pamoate | Alternative | 11 mg/kg of pyrantel base (up to 1 g) | ||
Pinworm | Albendazole | First line | 400 mg once and repeat dose in 2 weeks | |
Pyrantel pamoate | Alternative | 11 mg/kg of pyrantel base (up to 1 g); repeat in 2 weeks | ||
Whipworm | Albendazole | First line | 400 mg for 3 days (7 days for high worm burden) | |
Ivermectin and albendazole | Alternative for high worm burden | Ivermectin 200 µg/kg single dose and albendazole 400 mg single dose | ||
Ivermectin | Alternative | 200 µg/kg every day for 3 days | ||
Nitazoxanide | Alternative | 500 mg for 3 days | 1-3 yearsb: 100 mg twice daily for 3 days | |
4-11 yearsb: 200 mg twice daily for 3 days | ||||
Intestinal trematodes | ||||
Fasciolopsis buski; Heterophyes heterophyes; Metagonimus yokogawai; Nanophyteus salmincola | Praziquantel | First line | 25 mg/kg 3 times daily for 1 day | |
Intestinal cestodes (tapeworm) | ||||
Taenia saginata (beef), Taenia solium (pork), Diphyllobothrium latum (fish), Dipylidium canium (dog) | Praziquantel | First line | 5-10 mg/kg single dose | ≥4 yearsc: 5-10 mg/kg single dose |
Nitazoxanide | Alternative | 500 mg twice a day for 3 days | 1-11 yearsb: 7.5 mg/kg (100 or 200 mg) twice a day for 3 days ≥12 years: 500 mg twice a day for 3 days |
|
Hymenolepis nana (dwarf tapeworm) | Praziquantel | First line | 25 mg/kg single dose | |
Nitazoxanide | Alternative | 500 mg twice a day for 3 days | 1-11 yearsb: 7.5 mg/kg (100 or 200 mg) twice a day for 3 days | |
≥12 years: 500 mg twice a day for 3 days |
Table only includes agents commercially available in the United States.
Dosage varies depending on indication and reference; oral suspension only for <12 years.
Case reports exist with safe and efficacious use as young as 2 weeks of age.8