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. 2018 Apr 7;8(3):432–439. doi: 10.1016/j.apsb.2018.03.003

Table 1.

Pharmacokinetics parameters of monolayer films and sandwich films.

Parameter	Monolayer film^a	Sandwich film^a
C_max (μg/mL)	1.546±0.462	0.981±0.185^*
T_max (h)	1	4±2.739^*
AUC_0−t (μg/mL·h)	49.941±2.757	49.724±2.568
MRT₀_−t (h)	343.902±37.413	257.563±65.14^*
t_1/2 (h)	295.012±35.56	492.247±282.739

^a

Data are mean±SD, n=5.

^*

P<0.05, compared with monolayer films.