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. 2018 May 2;10(5):902–929. doi: 10.18632/aging.101438

Table 4. Associations between selected markers of atherosclerosis and the concentrations of testosterone (T) or dihydrotestosterone (DHT) in blood serum or plasma.

Associated variables Coefficient
of association
(RS)
Value of a posteriori probablility
(P)
testosterone
total cholesterol
-0.264 (-0.056) 0.0005 (0.244)
m -0.073 0.182
f 0.115 0.077
triglycerides -0.038 (-0.023) 0.316 (0.388)
m -0.031 0.350
f 0.054 0.251
HDL cholesterol -0.322 (-0.035) <<0.0001 (0.331)
m -0.073 0.182
f 0.018 0.414
LDL cholesterol -0.177 (-0.092) 0.014 (0.127)
m -0.040 0.313
f 0.165 0.020
fasting glycaemia 0.223 (0.189) 0.003 (0.009)
m 0.241 0.001
f 0.142 0.039
uric acid 0.411 (0.220) <<0.0001 (0.003)
m 0.141 0.040
f 0.307 <<0.0001
homocysteine 0.234 (0.040) 0.002 (0.311)
m 0.224 0.003
f -0.127 0.057
dihydrotestosterone
total cholesterol
-0.252 (-0.059) 0.001 (0.233)
m -0.037 0.323
f 0.096 0.118
triglycerides -0.040 (-0.017) 0.311 (0.417)
m -0.001 0.496
f 0.042 0.304
HDL cholesterol -0.304 (-0.016) 0.0001 (0.422)
m -0.050 0.267
f 0.025 0.378
LDL cholesterol -0.173 (-0.083) 0.016 (0.152)
m -0.015 0.425
f 0.122 0.066
fasting glycaemia 0.225 (0.185) 0.002 (0.011)
m 0.224 0.003
f 0.158 0.025
uric acid 0.403 (0.206) <<0.0001 (0.005)
m 0.127 0.058
f 0.333 <<0.0001
homocysteine 0.196 (0.024) 0.007 (0.383)
m 0.192 0.008
f -0.210 0.004

Associations, estimated in the group composed of 73 men and 82 women, are presented as the LOO-boosted non-adjusted or sex-adjusted Spearman’s rank correlation coefficients; the values adjusted for sex, given in parentheses, were calculated with the partial Spearman’s correlation analysis. Spearman correlation coefficients, calculated separately for men (m) and women (f), were estimated by bootstrap resampling with replacement adjusted for the sample size of the overall group (n=155) (10000 iterations). LOO, the leave-one-out (‘jackknife’ or ‘d-jackknife’) algorithm.