Table 1. The significant changes of E2Fs expression in transcription level between different types of lung cancer and lung tissues (ONCOMINE database).

	Types of lung cancer vs. lung	Fold change	P value	t-test	Ref
E2F1	Lung Adenocarcinoma vs. Normal	2.142	2.79E-06	6.168	Garber [26]
	Squamous Cell Lung Carcinoma vs. Normal	2.084	2.21E-05	5.658	Garber [26]
E2F2	Lung Adenocarcinoma vs. Normal	2.238	1.12E-14	9.707	Selamat [27]
E2F3	Squamous Cell Lung Carcinoma vs. Normal	2.066	1.66E-13	9.337	Talbot [25]
	Lung Adenocarcinoma vs. Normal	3.002	7.14E-05	4.733	Bhattacharjee [24]
	Small Cell Lung Carcinoma vs. Normal	4.391	7.16E-06	5.632	Bhattacharjee [24]
	Large Cell Lung Carcinoma vs. Normal	2.338	4.91E-06	5.904	Hou [22]
E2F4	NA	NA	NA	NA	NA
E2F5	Lung Adenocarcinoma vs. Normal	4.085	9.91E-05	4.576	Bhattacharjee [24]
	Lung Adenocarcinoma vs. Normal	2.208	1.51E-06	5.984	Stearman [28]
E2F6	NA	NA	NA	NA	NA
E2F7	Squamous Cell Lung Carcinoma vs. Normal	7.296	1.46E-13	12.969	Hou [22]
	Large Cell Lung Carcinoma vs. Normal	4.243	1.20E-05	5.597	Hou [22]
E2F8	Lung Adenocarcinoma vs. Normal	5.779	4.87E-11	8.272	Su [23]
	Lung Adenocarcinoma vs. Normal	3.659	1.51E-12	9.277	Hou [22]
	Large Cell Lung Carcinoma vs. Normal	4.707	2.43E-06	6.356	Hou [22]
	Squamous Cell Lung Carcinoma vs. Normal	2.48	4.96E-10	8.722	Hou [22]