Figure 4.
Detection of Ebola virus with optical-fiber based fluorometer. Calibration curve showing the relationship between the target concentrations and fluorescence intensity on a logarithmic scale. RNase-free water background signal was subtracted from both of the positive and negative signals. The limit of detection of the Ebola virus in blood with the 10× on-chip concentration protocol is ∼800 aM determined with a positive-to-negative signal ratio of ∼3:1. Error bars are standard error of the mean.