Table 4.
Unadjusted associations between each patient characteristic and health-related quality of life scores
| Characteristic | Estimate | SE | P† |
|---|---|---|---|
| Socio-demographic | |||
| Participant age | 0.411 | 0.151 | 0.007 |
| Married | 1.436 | 2.765 | 0.6 |
| Caucasian race | −0.322 | 4.381 | 0.9 |
| College graduate | 5.263 | 2.528 | 0.04 |
| Household income >$50,000 | 7.055 | 2.613 | 0.008 |
| Employed | 9.148 | 2.333 | 0.0001 |
| Religious faith “very important” | 2.432 | 2.341 | 0.3 |
| Live in United States | 3.494 | 3.762 | 0.4 |
| Illness-related | |||
| Duration of metastatic illness | 0.281 | 0.464 | 0.5 |
| De novo metastatic cancer | 1.314 | 2.242 | 0.6 |
| Breast cancer | 4.241 | 4.035 | 0.3 |
| Academically-affiliated practice | −3.545 | 2.246 | 0.1 |
| Karnofsky Performance Status score | 0.861 | 0.069 | <0.0001 |
| Life extension goal of treatment | 0.534 | 2.291 | 0.8 |
| Clear prognostic understanding | 10.271 | 2.880 | 0.0004 |
| Mood symptoms | |||
| Depression | −1.307 | 0.100 | <0.001 |
| Anxiety | −0.736 | 0.103 | <0.001 |
| Parenting-related | |||
| PCQ score | −13.849 | 1.233 | <0.0001 |
| Number of children | −0.723 | 1.023 | 0.5 |
| Age of children <18 years | 0.107 | 0.264 | 0.7 |
| Age of youngest child | 0.173 | 0.233 | 0.5 |
| Presence of another caregiver for children | 2.512 | 2.618 | 0.3 |
| Parental status influences treatment | −7.050 | 3.918 | 0.0733 |
| Have not discussed prognosis with children | −7.412 | 2.453 | 0.003 |
| Children not old enough to have discussion | −1.245 | 3.095 | 0.7 |
| Concerned about financial impact on children | −5.842 | 2.179 | 0.008 |
†
Age of children ≥18 years not included in calculation
Abbreviations: PCQ=Parenting Concerns Questionnaire (range 1–5, higher scores indicate more concerns)