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. Author manuscript; available in PMC: 2019 May 1.
Published in final edited form as: J Orthop Res. 2018 Jan 10;36(5):1356–1369. doi: 10.1002/jor.23834

Table 3.

Significant extracellular matrix related genes enriched in annulus fibrosus and nucleus pulposus

Genes enriched in nucleus pulposus Genes enriched in nucleus pulposus
CCBE1 collagen and calcium binding EGF domains 1 ACAN aggrecan
CNTN1 contactin 1 CHI3L1 chitinase 3 like 1
CNTNAP3B contactin associated protein-like 3B CHRD chordin
COL14A1 collagen type XIV alpha 1 chain COL10A1 collagen type X alpha 1 chain
COL17A1 collagen type XVII alpha 1 chain COL11A1 collagen type XI alpha 1 chain
COL18A1 collagen type XVIII alpha 1 chain COL8A2 collagen type VIII alpha 2 chain
COL21A1 collagen type XXI alpha 1 chain COL9A2 collagen type IX alpha 2 chain
COL24A1 collagen type XXIV alpha 1 chain CRTAC1 cartilage acidic protein 1
COL4A1 collagen type IV alpha 1 chain FMOD fibromodulin
DLL1 delta like canonical Notch ligand 1 FN1 fibronectin 1
DTX1 deltex E3 ubiquitin ligase 1 GPC6 glypican 6
DTX4 deltex E3 ubiquitin ligase 4 HHIPL1 HHIP like 1
EGFLAM EGF like, fibronectin type III and laminin G domains HHIPL2 HHIP like 2
JAG1 jagged 1 LAMC3 laminin subunit gamma 3
JAG2 jagged 2 LTBP2 latent transforming growth factor beta binding protein 2
LAMA3 laminin subunit alpha 3 LUM lumican
LAMA4 laminin subunit alpha 4 OGN osteoglycin
LAMA5 laminin subunit alpha 5 PRG4 proteoglycan 4
NOTCH3 notch 3 SDC4 syndecan 4
NOTCH4 notch 4 SRPX2 sushi repeat containing protein, X-linked 2
PDGFB platelet derived growth factor subunit B WISP3 WNT1 inducible signaling pathway protein 3