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. Author manuscript; available in PMC: 2018 Jun 7.
Published in final edited form as: Proteomics. 2018 May 15;18(11):e1700475. doi: 10.1002/pmic.201700475

Figure 4. Nicotine-induced protein alterations within and between cell lines.

Figure 4

A) Venn diagram of proteins with statistically significant nicotine-induced up-regulation in α7KO and HAP1wt cell lines. B) Modified dot plot of proteins (n=6) that are of higher abundance in α7KO but not in HAP1wt cell lines (top), proteins (n=16) of higher abundance in both cell lines (middle), and proteins (n=33) of higher abundance in HAP1wt, but not in α7KO cell lines (bottom). Data points represent the average relative abundance measurement for nicotine-treated cells divided by that for untreated cells. Error bars represent standard deviations. Dashed yellow line represents the nicotine-to-control ratio of 1.5. C) The KEGG pathway categories that are enriched by the associated proteins listed on the right.