Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Dec 14;7(1):59–85. doi: 10.1007/s40120-017-0086-4

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2017

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

PMC Copyright notice

Fig. 5 — Magnetic resonance imaging outcomes associated with quintiles of vitamin D in the EPIC study. EPIC is a 5-year longitudinal MS cohort study at the University of California at San Francisco, USA. Participants (N = 469) had clinical evaluations, brain MRI, and blood draws annually. MRI outcomes were associated with quintiles of vitamin D. In multivariate analyses, each 10 ng/mL (25 nmol/L) higher 25-hydroxyvitamin D level was associated with a 15% lower risk of a new T2 lesion (incidence rate ratio [IRR],0.85; 95% confidence interval [CI], 0.76–0.95; P = 0.004) and a 32% lower risk of a gadolinium-enhancing lesion (IRR, 0.68; 95% CI, 0.53–0.87; P + 0.002).

Reprinted with permission from Wiley Company [53]