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. 2017 Dec 14;7(1):59–85. doi: 10.1007/s40120-017-0086-4

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© The Author(s) 2017

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 6 — Multiple sclerosis outcomes according to dichotomous serum 25(OH)D levels. Analyses are based on patients with averaged 6- and 12-month measurements of 25(OH)D. Group comparisons are adjusted for age, sex, treatment, time of follow-up, and T2 lesion score at baseline. The graphs show the probability of conversion to CDMS after 12 months (a); the cumulative number of new active lesions on brain MRI (b); the percentage change in T2 lesion volume from year 1 to year 5 on brain MRI (c); and the percentage change in brain volume from year 1 to year 5 (d). The error bars indicate the standard error of the mean (SEM).

Reproduced with permission from [60]. Copyright©2014 American Medical Association. All rights reserved