Skip to main content
. 2018 Feb 25;32(6):1317–1326. doi: 10.1038/s41375-018-0075-3

Fig. 4.

Fig. 4

123b-33bcCAR T-cells demonstrate a profound anti-leukemic effect against MOLM13 and U937 cell lines in two in vivo xenograft mouse models. a Mouse model using MOLM13 cells to induce measurable tumor formation. Mice treated with either 123b-33bcCAR T-cells or control T-cells. Tumor burden visualized on days 3, 6, 9, and 13 (left panel) with b graphical representation on the right. c Log-rank Mantel–Cox test shows significance for improved experimental group survival (P = 0.0082). d Mouse model using U937 cells to induce measurable tumor formation. Mice treated with either 123b-33bcCAR T-cells or control T-cells. Tumor burden visualized on days 3, 6, 9, and 13 (left panel) with e graphical representation on the right. f Log-rank mantel-cox test shows significance for improved experimental group survival (P = 0.0082)