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. 2018 Feb 25;32(6):1317–1326. doi: 10.1038/s41375-018-0075-3

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — Depletion of infused 123b-33bcCAR T-cells following treatment with alemtuzumab. a Experimental schema to evaluate the effect of alemtuzumab administration after 123b-33bcCAR T-cells infusion into NGS mice. b Representation of 123b-33bcCAR T-cells persistence in peripheral blood 6 h later. Presence of 123b-33bcCAR T-cells was detected by flow cytometry. c Representation of persistence of infused 123b-33bcCAR T-cells in peripheral blood 24 h later. Presence of 123b-33bcCAR T-cells was detected by flow cytometry