Table 1.

Questions and answer options used as outcome variable and determinants

Variable	Question	Answer options	Type of variable in analyses	Analyses of HCPs/patients
Outcome variable
App interest	In general, how interested would you be in an app of the <national medicines agency> that you can use for both, reporting side effects/adverse drug reactions and receiving safety information?	Not interested at all Somewhat interested Interested Very interested Don’t know	Dichotomous: not/(somewhat) interested vs. very interested Don’t know → excluded	HCPs and patients
Determinants
Age	What is your age?	Continuous	Continuous	HCPs and patients
Gender	What is your gender?	Male Female Other/prefer not to say	Dichotomous: male vs. female Other/prefer not to say → excluded	HCPs and patients
Educational level	What is your highest level of education completed?	No formal education or below Primary education Lower secondary education Upper secondary education Post-secondary but non-tertiary education First stage of tertiary education Second stage of tertiary education	Dichotomous: low/secondary education vs. tertiary education (first and second stage)	Patients
Number of medicines	How many different medicines are prescribed to you at the moment?	0 1 2 3 4 5 or more	Categorical: 0 medicines; 1–4 medicines (reference category); ≥  5 medicines	Patients
Use health apps	How often do you use a health app?	Daily Weekly Monthly or less often Never	Dichotomous: never vs. other answer options	HCPs and patients
Experience of ADRs	Have you ever experienced a side effect of a medicine that you take or have taken in the past?	Yes No Don’t know/don’t remember	Dichotomous: no/don’t know vs. yes	Patients
Awareness of reporting ADRs	Are you aware that you can report experienced side effects to the <national medicines agency>?	Yes No I have never heard of the <national medicines agency>	Dichotomous: no/I have never heard of the <national medicines agency> vs. yes	Patients
Report ADR to national medicines agency	Have you ever reported an adverse drug reaction experienced by your patients to the <national medicines agency>?	Yes No Don’t know/don’t remember	Dichotomous: no/don’t know vs. yes	HCPs

ADR adverse drug reaction, HCPs healthcare professionals