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. 2018 Apr 24;40(7):1029–1036. doi: 10.1007/s10529-018-2556-x

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 2 — Concentration of the electrolytes Na⁺ (a), K⁺ (b), and Ca²⁺ (c) depending on the relative evaporation (filled square), respective linear correlations (line) during a batch culture with GS-CHO cells grown in the micro-Matrix. The shaking speed was set to 220 rpm at a working volume of 3.5 mL. The DO was controlled at 30% and the pH at 7.2. Na⁺: y = 0.56·x − 60.4, R² = 0.95; K⁺: y = 6.94·x − 55.6, R² = 0.92; Ca²⁺: 42.9·x + 2.1, R² = 0.45. Error bars represent one standard deviation about the mean (n = 3)