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. 2018 May 31;10:142. doi: 10.3389/fnagi.2018.00142

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Copyright © 2018 Smith, Yao, Chen and Kirby.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Body weight increased over the course of housing but did not differ between group- and pair-housed mice. Two-way RM-ANOVA: main effect of week (p < 0.0001), main effect of housing (p = 0.798), trial by housing interaction (p = 0.840), effect of subjects (p < 0.0001). Each point represents average ± SEM. (B) Fecal corticosterone metabolite levels were similar between pair-housed cages and group-housed cages. Each point represents one cage. Average ± SEM is shown. (C) Plasma corticosterone did not differ between group- and pair-housed mice. Unpaired Welch’s test, p = 0.553. Each point represents one mouse. Average ± SEM is shown.