Table 1.
Comparisons of demographic characteristics and parameter of alpha diversity between cancer patients and non-cancer controls.
Cancer (n = 31) | Non-cancer (n = 18) | P-value | |
---|---|---|---|
DEMOGRAPHIC | |||
Age (y) | 64.0 (49.0, 69.0) | 55.5 (45.8, 64.8) | Ns |
BMI | 22.9 (20.8, 24.2) | 22.1 (20.1, 23.4) | Ns |
Smoking habit | 24 (77.4) | 7(38.9) | 0.007 |
Smoking index | 600 (50, 800) | 150 (0, 300) | 0.002 |
Drinking habit | 8 (25.8) | 8 (44.4) | Ns |
Hypertension | 10 (32.3) | 4 (22.2) | Ns |
Diabetes | 6 (18.2) | 1(5.6) | Ns |
Hyperlipidemia | 2 (6.5) | 2 (11.1) | Ns |
CHD | 3 (9.7) | 1 (5.6) | Ns |
FHC | 1 (3.0) | 0 (0) | Ns |
ALPHA DIVERSITY | |||
Number of reads | 105440.0 (83300.0, 107694.0) | 98289.0 (60820.0, 107601.0) | Ns |
Observed species | 120.0 (77.0, 147.0) | 56.0 (49.0, 107.3) | 0.008 |
Chao1 | 134.5 (82.5, 172.4) | 68.3 (54.4, 116.8) | 0.008 |
Ace | 139.6 (41650.0, 53847.0) | 72.9 (54.9, 111.9) | 0.003 |
Shannon | 2.4 (1.6, 2.9) | 2.3 (1.8, 2.8) | Ns |
Simpson | 0.2 (0.1, 0.4) | 0.2 (0.1, 0.3) | Ns |
Data were presented as median (first quartile to the third quartile) for continuous variables or n (%) for counts. BMI, body mass index; CHD, coronary atherosclerotic heart disease; FHC, family history of cancer; Ns, not significant (based on P < 0.05).