Table 1. Population Characteristics.
Author | BMMC (n) | Control (n) | Follow-up (month) | Doses | Injection time | Aspiration to injection | Infarcted territory | Imaging |
---|---|---|---|---|---|---|---|---|
Assmus, et al.12 | 91 | 85 | 4 | 198×106 | 3–7 days | Same day | - | Angiography |
Beitnes, et al.13 | 50 | 50 | 3, 6, 12, 36 | 68×106 | 4–8 days | Same day | Anterior wall | ECHO |
Benedek, et al.14 | 9 | 9 | 48 | 1.66±0.32×109 | 3 weeks–3 months | Same day | Anterior wall | Angiography |
Cao, et al.15 | 41 | 45 | 1, 3, 6, 12, 48 | 5±1.2×107 | 7 days | Same day | Anterior wall | ECHO |
Colombo, et al.16 | 5 | 5 | 12 | 5.9×106 | 10–14 days | Same day | Anterior wall | ECHO |
Dill, et al.17 | 27 | 27 | 4, 12 | 236±174×106 | 3–8 days | Same day | - | MRI |
Hirsch, et al.18 | 66 | 69 | 4 | 296±164×106 | 3–8 days | Same day | Anterior wall | MRI |
Hu, et al.19 | 11 | 14 | 6, 12 | 10×107 | Day 5 | 24 h after harvested | Anterior wall | ECHO |
Huang, et al.20 | 26 | 25 | 6, 12 | 4.9×108 | 3–7 days, 7–30 days | Same day | Anterior wall | ECHO |
Huikuri, et al.21 | 40 | 40 | 6 | 360×106 | 2–6 days | Same day | Anterior wall | ECHO |
Janssens, et al.22 | 33 | 34 | 4 | 304×106 | Within 24 hours | Same day | Anterior wall | MRI |
Lunde, et al.23 | 50 | 50 | 6 | 68×106 | 4–8 days | 24 h after harvested | Anterior wall | SPECT |
Meyer, et al.24 | 30 | 30 | 6, 18 | 24.6±9.4×108 | 4.8±1.3 days | Same day | Anterior wall | MRI |
Piepoli, et al.25 | 19 | 19 | 1, 6, 12 | 418×106 | 4±1 days | Same day | Anterior wall | Rest SPECT |
San Roman, et al.26 | 30 | 31 | 12 | 83×106 | 3–5 days | Same day | Anterior wall | MRI/angiography |
Schaefer, et al.27 | 30 | 29 | 6, 18 | 25±2×109 | Within 5 days | Same day | Anterior wall | ECHO |
Skalicka, et al.28 | 17 | 10 | 4, 24 | 26.4×108 | 4–11 days | Same day | Anterior wall | ECHO |
Srimahachota, et al.29 | 11 | 12 | 6 | 420±221×106 | 57.2±122.8 days | Same day | - | MRI/ ECHO |
Tendera, et al.30 | 46 | 20 | 6 | 1.78×108 | 3-12 days | Same day | Anterior wall | MRI |
Traverse, et al.31 | 30 | 10 | 6 | 150×106 | 15.5–20 days | Same day | Anterior wall | MRI |
Wollert, et al.32 | 30 | 30 | 6 | 24±6×108 | 4–8 days | Same day | - | MRI |
Yao, et al.33 | 12 | 12 | 6, 12 | 1.9±1.2×108 | 3–7 days | Same day | Anterior wall | MRI |
BMMC, bone marrow mononuclear cells; MRI, magnetic resonance imaging; ECHO, echocardiography; SPECT, single photon emission computed tomography.