Table 2. Subgroup Analyses based on Imaging Modalities, Timing of Injection and Doses of Cells Infusion.

Outcomes		Subgroup	No. of studies	Effect estimate	p values
LVEF	Modalities	MRI	11	2.37 (0.87, 3.86)	0.002
		ECHO	8	2.69 (0.28, 5.10)	0.03
		Angiography	2	1.88 (0.30, 3.46)	0.02
		SPECT	1	6.00 (4.25, 7.75)	<0.001
	Doses	<108	4	2.77 (1.29, 4.26)	0.0002
		108–109	13	2.67 (1.21, 4.13)	0.0003
		>109	5	3.01 (−0.48, 6.49)	0.09
	Timing	Within 24 hours	2	3.03 (−0.19, 6.24)	0.06
		2–14 days	18	2.97 (1.58, 4.37)	<0.001
		>14 days	4	0.76 (−1.09, 2.61)	0.42
LVEDV	Modalities	MRI	11	−2.12 (−6.03, 1.79)	0.29
		ECHO	7	−1.68 (−4.37, 1.01)	0.22
		Angiography	2	−6.43 (−19.51, 6.64)	0.31
		SPECT	1	−23.50 (−32.11, -14.89)	<0.001
	Doses	<108	4	−2.64 (−7.19, 1.91)	0.26
		108–109	12	−6.23 (−11.73, -0.73)	0.03
		>109	5	−0.19 (−3.11, 2.72)	0.90
	Timing	Within 24 hours	2	−1.67 (−7.50, 4.16)	0.57
		2–14 days	17	−2.91 (−6.00, 0.19)	0.07
		>14 days	4	−8.90 (−22.24, 4.44)	0.19
LVESV	Modalities	MRI	11	−3.32 (−5.64, -1.00)	0.005
		ECHO	5	−5.47 (−12.11, 1.17)	0.11
		Angiography	2	−4.15 (−9.30, 1.01)	0.11
		SPECT	1	−12.00 (−16.95, -7.05)	<0.001
	Doses	<108	2	−6.28 (−9.85, -2.71)	0.0006
		108–109	13	−5.99 (−9.21, -2.77)	0.0003
		>109	4	0.29 (−2.16, 2.74)	0.82
	Timing	Within 24 hours	2	−7.58 (−19.71, 4.56)	0.22
		2–14 days	16	−5.11 (−7.83, -2.39)	0.0002
		>14 days	3	−3.76 (−9.31, 1.79)	0.18

LVEF, left ventricular ejection fraction; LVEDV, left ventricular end-diastolic volume; LVESV, left ventricular end-systolic volume; MRI, magnetic resonance imaging; ECHO, echocardiography; SPECT, single photon emission computed tomography.