Figure 2.

The probability of having LVDD curvilinearly increased with age (A). r_age and r_age2 are the partial correlation coefficients for the linear and squared terms of age and P_age and P_age2 the corresponding significance levels. R² is the coefficient of multiple determination. In panel A, red and blue dots indicate women and men, respectively. The full line represents the regression slope, and the dotted lines represent the 95% confidence boundaries for the prediction of the mean probabilities (blue) and individual probabilities (red) of LVDD at any given age. The odds of having LVDD in relation to HF1 weakened as covariables were stepwise introduced in the logistic model but remained significant after full adjustment (B). Odds ratios are expressed for a 1-standard deviation increment in HF1. The shaded area denotes the 95% confidence boundary of the parameter estimates. Stepwise cumulative were implemented for sex, age, BMI, SBP, DBP, heart rate (HR), serum creatinine (Crt), fasting blood glucose (Glyc), and treatment with inhibitors of the renin system (RAS) and β-blockers (BB).