Table 3.
In vitro antibacterial screening for compounds (3a–3i).
| microorganisms used for antibacterial activity (MIC µg ml−1) |
|||||
|---|---|---|---|---|---|
| Gram positive |
Gram negative |
||||
| products | R | B. subtilis | S. aureus | E. coli | P. aeruginosa |
| 3a | 5,7-diCH3 | 12.5 | 3.125 | 6.25 | 50 |
| 3b | 6-ter-butyl | 100 | 12.5 | 25 | 12.5 |
| 3c | 6-OCH3 | 6.25 | 3.125 | 25 | 100 |
| 3d | 6-CH3 | 12.5 | 25 | 50 | 50 |
| 3e | 6-Cl | 6.25 | 0.78 | 25 | 50 |
| 3f | 7-OH | 25 | 12.5 | 12.5 | 25 |
| 3g | 7-CH3 | 25 | 50 | 100 | 25 |
| 3h | 5,6-benzo | 25 | 3.125 | 12.5 | 12.5 |
| 3i | 7,8-benzo | 12.5 | 1.562 | 50 | 50 |
| ciprofloxacina | 6.25 | 6.25 | 3.125 | 6.25 | |
aCiprofloxacin was used as a positive control against bacteria species.