Table 1.
Frequencies of treatment naïve leprosy patients with or without reactions during or after MDT, divided according to their operational classification, gender, Mitsuda test result, anti-phenolic glycolipid 1 (PGL-1) IgM serology, and anti-lipoarabinomannan (LAM) sIgA in saliva, obtained at diagnosis.
| Variables | Leprosy reactions |
Odds ratio | Confidence interval (95%) | P | ||||
|---|---|---|---|---|---|---|---|---|
| Yes |
Total (n) | |||||||
| n | (%) | |||||||
| Operational classification | ||||||||
| Multibacillary (MB) | 41 | (52.6) | 78 | 4.15 | 1.69–10.19 | 0.001 | ||
| Paucibacillary (PB) | 8 | (21.1) | 38 | |||||
| Gender/operational classification | ||||||||
| Male | 72 | MB | 24 | (45.3) | 53 | 4.41 | 1.14–16.96 | 0.030 |
| PB | 3 | (15.8) | 19 | |||||
| Female | 44 | MB | 17 | (68) | 25 | 5.95 | 1.58–22.32 | 0.008 |
| PB | 5 | (26.3) | 19 | |||||
| Total | 49 | (42.2) | 116 | |||||
| Mitsuda | ||||||||
| 0–7 mm | 16 | (35.6) | 45 | 2.34 | 0.67–8.17 | 0.181 | ||
| >7 mm | 4 | (19.0) | 21 | |||||
| Anti-PGL-1 IgM | ||||||||
| PGL-1+ | 32 | (54.2) | 59 | 2.78 | 1.29–5.98 | 0.008 | ||
| PGL-1− | 17 | (29.8) | 57 | |||||
| Anti-LAM sIgA | ||||||||
| LAM+ | 34 | (50.7) | 67 | 2.33 | 1.07–5.06 | 0.031 | ||
| LAM− | 15 | (30.6) | 49 | |||||
Mitsuda test reading system: “negative” for readings up to 7 mm (0–7 mm) and “positive” for readings greater than 7 mm (>7 mm) (17). P, probability value.
Bold fonts were used to emphasize the significant values.