Table 2.

Determinants for persistent asthma and COPD at follow up by logistic regression in 239 individuals with asthma at baseline.

	Follow up
	Persistent asthma, OR (95%CI)			COPD, OR (95%CI)
Determinants, Baseline	All (n = 164)	Early-onset asthma (n = 74)a	Late-onset asthma (n = 81)a	All (n = 35)	Early-onset asthma (n = 16)b	Late-onset asthma (n = 15)b
Sex, female	0.70 (0.35–1.40)	0.69 (0.17–2.83)	0.70 (0.26–1.84)	1.43 (0.61–3.38)	20.40(1.57–265.69)	0.71 (0.15–3.33)
FEV₁ below pred	2.12 (0.98–4.61)	7.12(1.61–31.50)	1.53 (0.53–4.40)	3.05 (0.67–13.91)	2.91 (0.23–37.35)	NA
Bronchial hyperresponsiveness	1.01 (0.51–2.00)	2.18 (0.36–13.21)	1.13 (0.43–2.97)	0.79 (0.35–1.81)	0.06(0.01–0.56)	3.04 (0.68–13.70)
ACOS	2.60 (0.89–7.62)	2.81 (0.23–34.00)	1.27 (0.29–5.63)	6.98(2.84–17.14)	204.96(9.20–4566.65)	15.53(3.22–74.76)
Asthma Score per step increase.	1.21 (0.94–1.56)	2.06(1.15–3.68)	1.12 (0.80–1.56)	1.03 (0.78–1.37)	1.39 (0.81–2.39)	0.84 (0.52–1.34)
Medication, 12 mth
SABA only	3.39(1.47–7.82)	4.52 (0.81–25.22)	2.26 (0.69–7.42)	0.90 (0.27–2.99)	5.06 (0.60–42.67)	0.25 (0.02–2.84)
ICS and/or LABA	8.95(3.87–20.69)	9.87(1.95–49.98)	6.84(2.09–22.37)	1.22 (0.41–3.59)	0.38 (0.05–3.19)	1.29 (0.19–8.67)
Current smoking	0.45(0.21–0.94)	1.01 (0.20–5.15)	0.98 (0.35–2.72)	1.86 (0.74–4.70)	4.54 (0.67–30.53)	2.25 (0.51–10.00)
High-risk occupation (asthma) c	2.48 (0.45–13.72)	1.18 (0.04–33.77)	1.97 (0.26–14.90)	0.35 (0.03–3.59)	NA	0.08 (0.00–2.33)
High-risk occupation (COPD)d	0.53 (0.10–2.87)	1.25 (0.04–36.31)	0.57 (0.08–4.15)	1.93 (0.20–18.83)	NA	7.78 (0.31–197.17)

Bold values denote significant associations (p < 0.05).

^an (total) = 155 due to missing data on age at first asthma attack.

^bn (total) = 31 due to missing data on age at first asthma attack.

^cn = 236; 3 participants had missing in variable ‘high-risk occupation (asthma)’.

^dn = 236; 3 participants had missing in variable ‘high-risk occupation (COPD)’.

NA: Not applicable

The table shows odds ratios (OR) with 95% confidence intervals (95% CI).