Fig. 3.

Diagnostic criteria: margins. Margins can be either circumscribed or not circumscribed. Circumscribed margins indicate a benign lesion and are more regularly found in mass (A) than in non-mass (B) lesions. Non-circumscribed margins include irregular (C: mass lesion, D: non-mass lesion), hinting at an intermediate risk of breast cancer, and spiculated. Spiculated margins (E: mass lesions, F: non-mass lesion) are highly suggestive of malignancy. Note that the most suspicious criterion applies; thus, single spiculae in an otherwise circumscribed lesion constitute spiculated margins. This is why this criterion was named the “root sign” by Kaiser