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. 2018 May 15;9(3):313–324. doi: 10.1007/s13244-018-0628-z

Fig. 7.

Fig. 7

Methotrexate neurotoxicity. (acute phase). A 14-year-old girl with acute lymphocytic leukaemia, who received intrathecal methotrexate, presented with left hemiplegia. a Diffusion-weighted image shows a small area of hyperintensity within the right centrum semiovale (arrow). b Apparent diffusion coefficient map shows restricted diffusion in this lesion (arrow)