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. 2018 May 31;9:547. doi: 10.3389/fphar.2018.00547

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Copyright © 2018 Yuan, Du, Liu, Ma, Zhang, Du and Cai.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Exosomes derived from stem cells have proposed for cardiac disease therapy. Exosome derived from different types of stem cells, including embryonic stem cells (ESC), induced pluripotent stem cells (iPSCs), heart-derived stem cells and mesenchymal stem cells (MSCs) deliver nucleic acids (DNAs/RNAs) and proteins to the damaged heart tissue consequently exert cardioprotective effects.