Skip to main content
. Author manuscript; available in PMC: 2018 Jun 7.
Published in final edited form as: ChemMedChem. 2018 Apr 16;13(9):968–979. doi: 10.1002/cmdc.201800031

Figure 2.

Figure 2

cG8 and mTTR retain TTR,s ability to inhibit Aβ aggregation. Aβ monomer was combined with either TTR (A), cG8 (B), or mTTR (C) and aggregated at 37°C for 48 h. All samples contained 28 μM Aβ with inhibitor/Aβ molar ratio of 1:20 (black), 1:50 (dark grey), or 1:75 (light grey) and are compared to Aβ alone (white). Aggregation was monitored via ThT fluorescence and data was blank (ThT in PBS) subtracted then normalized to the fluorescence of the control at 48 h. Error bars indicate SEM, n=3–4 for samples, n=8 for control. *p<0.05 vs. control.